The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer): A Multinational, Randomized, Open-label Phase 3 Study of MEK162 vs. Physician’s Choice Chemotherapy in Patients with Recurrent or Persistent Low-grade Serous Carcinomas of the Ovary, Fallopian Tube or Primary Peritoneum
A Phase 3 Randomized Double-Blind Trial of Maintenance with Niraparib Versus Placebo in Patients with Platinum Sensitive Ovarian Cancer
TRINOVA – A Phase 3 Randomized, Double-blind, Placebo-controlled, Multicenter Study of AMG 386 With Paclitaxel and Carboplatin as First-line Treatment of Subjects With FIGO Stage III-IV Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers.
Phase II Randomized Open Label Study of MM-121 in Combination With Paclitaxel Versus Paclitaxel Alone in Patients With Platinum Resistant/ Refractory Advanced Ovarian Cancers.
Phase II-III Study of intraperitoneal (IP) plus intravenous (IV) chemotherapy versus IV carboplatin plus Paclitaxel in patients with ovarian epithelial carcinoma subjected to optimum cytoreductive surgery subsequent to neoadyuvant intravenous chemotherapy.
Phase II trial to evaluate the efficacy and safety of catumaxomab as a consolidation treatment for patients with an ovarian or fallopian tube epithelial carcinoma, or a primary peritoneal carcinoma in second or third complete clinical remission.
Phase III study, multicentric, randomized, double-blind to evaluate the efficacy and security of BIBF 1120 in combination with carboplatin and paclitaxel compared with placebo combined with carboplatin and paclitaxel in patients with advanced ovarian cancer.
Phase II non-controlled, multi-center, prospective clinical trial to determine the clinical benefit and toxicity of Pazopanib, a multi-target inhibitor of receptors with tyrosine-kinase activity (VEGFR -1, -2 , -3, PDGFR-α and β and C-Kit), in platinum-resistant patients with advanced ovarian cancer.
Gynaecologic Cancer Intergroup double-blind, controlled, multicenter clinical trial of Cediranib (AZD 2171), in combination either with platinum-based chemotherapy or as the sole agent in maintenance therapy, in women with ovarian cancer who have relapsed over 6 months after termination of a platinum-based first-line treatment.
AURELIA: Phase III multi-centre, open, randomized clinical trial, with two treatment groups, of bevacizumab in combination with chemotherapy versus chemotherapy alone in patients with epithelial ovarian cancer or platinum-resistant fallopian tube or primary peritoneal carcinoma.
Phase III study to evaluate the efficacy and safety of pazopanib as monotherapy versus placebo amongst women with epithelial ovarian, fallopian tube or peritoneal primary cancer who have not progressed after first-line chemotherapy.
A single-arm Phase II clinical study of the combination of carboplatin and weekly periclitar plus bevacizumab as first-line treatment in patients with epithelial ovarian cancer.
Topotecan plus carboplatin versus the standard treatment (paclitaxel plus carboplatin or gemcitabine plus carboplatin) in the treatment of platinum-sensitive relapsing patients with peritoneal carcinoma, fallopian tube carcinoma or epithelial ovarian carcinoma.
Bevacizumab database in Ovarian Cancer relapses.
Retrospective study of biomarkers in Epithelial Ovarian Cancer.
Feasibility and toxicity of a modified outpatient regimen of intravenous/ intraperitoneal chemotherapy (IV/IP) in optimally debulked stage III ovarian cancer patients: A GEICO Study.
Multi-centre, randomized, two-arm “Gynaecologic Cancer InterGroup” study to add bevacizumab to standard chemotherapy (carboplatin and paclitaxel) in patients suffering from epithelial ovarian cancer.
Determination of the expression of TOPO IIA in ovarian carcinoma samples of patients treated with pegylated liposomal doxorubicin.
Multi-centre, randomized, double-blind, placebo-controlled clinical trial to evaluate maintenance treatment with abagovomab in patients suffering from epithelial ovarian carcinoma after complete response to first-line chemotherapy.
Phase II randomized study of the carboplatin-gemcitabine doublet followed by carboplatin-paclitaxel versus carboplatin-paclitaxel in platinum-sensitive relapse patients with ovarian carcinoma, primary peritoneal carcinomatosis or fallopian tube carcinoma.
Phase III clinical trial to evaluate treatment with the combination of cisplatin plus topotecan followed by paclitaxel plus carboplatin versus paclitaxel plus carboplatin as the first-line treatment in women with a recent diagnosis of advanced epithelial ovarian cancer.
Phase II study with Gemcitabine in prolonged infusion in patents with advanced platinum-resistant epithelial ovarian cancer.
Validation by GEICO of CAELYX in patients with epithelial ovarian cancer.
Phase II randomized clinical trial (with assessment of quality of life) of carboplatin versus the combination of taxol and carboplatin in platinum-sensitive patients with ovarian cancer relapse.
Randomized clinical trial of Paclitaxel / Epirubicin / Carboplatin in combination (TEC) vs. Paclitaxel / Carboplatin (TC) in the treatment of women with advanced ovarian cancer.